Chitosan/metal ion doped-bioactive glass coatings on Mg-alloys by electrophoretic deposition

 

Investigator: Felix Beyer (Master Student) Felix Beyer

 

Supervisors: Svenja Heise, Prof. Dr.-Ing. habil. Aldo R. Boccaccini


Due to its biodegradability the use of Magnesium as a temporary implant has the significant advantage of avoiding a second surgery for removal. In order to reduce and control the high corrosion rate of magnesium and its alloys and its subsequent consequences, protective coatings can be applied [1]. In this work a bioactive composite coating is developed via electrophoretic deposition (EPD) [2] on the magnesium alloy WE43. The coating is composed of chitosan and metal ion-containing bioactive glass nanoparticles, which showed in earlier studies very promising biological properties [3]. Initially the EPD parameters will be optimized and afterwards the mechanical, chemical and biological properties of the composite coating will be investigated.

[1] Svenja Heise, Michael Höhlinger, Yadir Torres Hernández, Juan José Pavón Palacio, Jose Antonio Rodriquez Ortiz, Victoria Wagener, Sannakaisa Virtanen, Aldo R. Boccaccini. Electrophoretic deposition and characterization of chitosan/bioactive glass composite coatings on Mg alloy substrates. Electrochimica Acta 232. 2017. 456–464.

[2] Aldo R. Boccaccini, et al., Electrophoretic deposition of biomaterials, J. Royal Soc. Interface. 7 Suppl 5. 2010. S581-613.

[3] Kai Zheng, Xinyi Dai, Miao Lu, Norbert Hüser, Nicola Taccardi, Aldo. R. Boccaccini. Synthesis of copper-containing bioactive glass nanoparticles using a modified Stöber method for biomedical applications. Colloids and Surfaces B: Biointerfaces 150. 2017. 159–167.