Influence of surface modifications on bone resorbing giant cells

 

Investigator: Frank Bayer (Master student) 

Frank Bayer

 

Supervisors: Dr.-Ing. Rainer Detsch, Prof. Aldo R. Boccaccini


One essential problem in the implantology is the appearance of infections caused by bacterial adhesion on the implant surface, which can lead to poor wound healing or, in serious cases, to rejection of the implant. This project focuses on the development of a bioactive and antibacterial coating for stainless steel (316 L), consisting of Copper doped bioactive glass and the natural protein zein, expanding from a previous study at the FAU Institute of Biomaterials [1]. The properties of the new coatings will be investigated by a range of techniques. Generally, surface characterization and mechanical testing of the layers followed by bioactivity and degradation studies after immersion in simulated body fluid will be carried out.

[1] Meyer, N. et al. Bioactive and antibacterial coatings based on zein/bioactive glass composites by electrophoretic deposition. Coatings 8, (2018) 27.