Processing, characterisation and applications of multifunctional mesoporous bioactive glass nanoparticles

 

Investigator: Dr.-Ing. Kai Zheng (Post Doc)Kai Zheng

Cauerstraße 6
91058 Erlangen

room 0.010

phone: +49 (0)9131 85-20807

email: kai.zheng@ww.uni-erlangen.de

 

Supervisor: Prof. Dr.-Ing. habil. Aldo R. Boccaccini

My main research project involves the development of smart platforms for effective, non-invasive, and highly targeted therapies to treat delayed bone healing and non-healing chronic skin wounds. For this purpose, solid and hollow mesoporous bioactive glass nanoparticles (MBGN) are being developed for controlled delivery of therapeutic agents [1]. Specific bioactive ions that can promote osteogenesis, angiogenesis and with antibacterial potential are bein considered to dope these MBGN to enhance bone regeneration or wound healing [2]. The project is being carried out in the framework of the EU funded project (“MOZART”) "MesopOrous matrices for localiZed pH-triggered releAse of theRapeuTic ions and drugs” (LINK: http://www.mozartproject.eu/).

[1] K. Zheng, A.R. Boccaccini, Sol-gel processing of bioactive glass nanoparticles: A review, Adv. Colloid Interface Sci. (2017) In Press.

[2] A. Hoppe, N.S. Güldal, A.R. Boccaccini, A review of the biological response to ionic dissolution products from bioactive glasses and glass-ceramics., Biomaterials. 32 (2011) 2757–2774.