Electrospun biopolymers for cardiac patches application

 

Investigator: Miao Geng (Master Student) Miao Geng

 

Supervisor: Florian Ruther, Prof. Dr.-Ing. habil. Aldo R. Boccaccini


Alginate-gelatine based hydrogels are being synthesized following a method developed at the FAU Institute of Biomaterials [1]. The properties of such hydrogels can be controlled through different relative proportions of the two components. Electrospinning will be applied to fabricate fibrous scaffolds from alginate-gelatine compositions. Such fibrous scaffolds will be characterized in terms of their degradation behaviour, mechanical properties and biological response for applications as cardiac patches.

[1] B. Sarker, D. G. Papageoriou, R. Sliva, T.Zehnder, F. Gul-E-Noor, M. Bertmer, J. Kaschta, K. Chrissafis, R. Detsch, and A. R. Boccaccini, "Fabrication of alginate-gelatin crosslinked hydrogel microcapsules and evaluation of the microstructure and physico-chemical properties," J.Mater, Chem.B, vol.2, no.11, p.1470, 2014.