Optimization of soy/alginate scaffolds containing bioactive glass for wound healing applications

 

Investigator: Pratishtha Mukoo (Bachelor student) 

Pratishtha Mukoo

 

Supervisors: Katharina Schuhladen, Prof. Aldo R. Boccaccini


Biomaterials are becoming increasingly important as they enable longer life expectancy and better quality of life. From the large pool of materials which can be used for wound healing applications, natural polymers are relevant due to their biocompatibility and cell adhesion properties. Soy is attractive in this field as it is of vegetable origin and available in abundance [1]. Alginate on the other hand is a well-known hydrogel, which was used as wound dressing material for decades. The aim of this study is to optimize soy/alginate-based scaffolds [3] containing bioactive glass for soft tissue engineering. The scaffolds will be characterized chemically and mechanically, and the degradation properties as well as the bioactivity will be examined.

[1] S. Tansaz, A. R. Boccaccini, Biomedical applications of soy protein: A brief overview, Journal of Biomedical Materials Research Part A 104 (2), (2016) 553-569.

[2] S. Tansaz, et al., Hydrogel films and microcapsules based on soy protein isolate combined with alginate, Journal of Applied Polymer Science 134 (2017) 44358.